Shinji mikami has revealed in a Famitsu interview bout his new game
It's called Zwei. It's a Survival Horror game which's Mikami's Directional Debut at Tango Gameworks.
Here's an Art :

Mikami said that “I’ve found my focus and once again I’m striving for pure survival horror. I am being very hands-on to see that the quality is there. Rest assured.”
I know i'm kinda late but I thought I should post this
But the SADDEST PART IS He said that this is the Last Game hes Directing -Cry-
I'm really looking forward to his Latest game, I'm pretty sure that his latest game'll
Beat Silent Hill, Dead Space and other horror games in terms of scariness.
After all, this Man has gave us gamers some of the AMAZING GAMES this industry needed(RE4,VANQUISH,GODHAND and many others).
So Uhh, Whaddya guys think ??
Source
http://www.digitaltrends.com/gaming/reside...rror-with-zwei/Details are pretty scarce at the moment, But I wish that we hear more at E3 2012